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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

2016年,中国电影票房经历了一次令人震惊的调整,从2015年的48%大幅下降到3.7%。
1.保险精算师

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

普京在国际记者年度新闻发布会上表示,他准备和任何一位当选的美国总统合作。
“而在市场上前所未有的是确实有客户在寻找这样的投资。”

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

Lecent was with an unknown number of other youth when she was killed by a single bullet inside a home in a public-housing complex near Martin Grove Rd. and Finch Ave W.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

corn

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 智能家居用户被黑的三大原因
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Others who made the top ten include Amazon's Jeff Bezos at fifth on the list, Mark Zuckerberg of Facebook at sixth, Oracle's Larry Ellison at seventh, Michael Bloomberg at eighth, and tied for ninth are David and Charles Koch.
['θ?:tful]
达洛伊西奥常喜欢说“时间是新的货币”。这是一个17岁男孩对人生的睿智洞察,也是Summly软件背后的发展理念。而我们多数人在他那个年龄,时间多得都不知道该怎么做才不会荒废。我很容易就忘了这样一个事实:达洛伊西奥在1995年出生于一个中上层阶级家庭,连高中都还没毕业,还住在小时候住的那个舒服卧室里。在我和他父母聊天的时候,他离开房间去在电脑上干活。只见他穿着袜子下楼,牛仔裤腿扫过大厅的地毯──此时此刻是他最像个孩子的时候。
Technically it is a project of the 10-member Association of Southeast Asian Nations to bring all of its trade deals in the region under one umbrella. It also lacks the ambition on many fronts of the TPP.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

swift
Paris (AFP) - Some 1,400 people living in France have either joined the jihadist cause in Syria and Iraq or are planning to do so, Prime Minister Manuel Valls said Monday.
A total of 61 IPOs were launched on the Shanghai and Shenzhen stock exchanges, down 67 percent on the same period last year. About 28.8 billion yuan (4.3 billion U.S.dollars) was raised, down by 80 percent.
Third, McDermott provides some protection against the possibility of Andre Roberson departing as a free agent in the summer.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Emerging market focused fund groups have endured a torrid year with sharply lower assets under management at Aberdeen and Ashmore. Emerging market exchange traded funds have also suffered heavy redemptions, with investors pulling $9.5bn from BlackRock’s iShares MSCI Emerging Markets and Vanguard’s FTSE Emerging Markets, according to ETF.com.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Wang said the journal and authors had an unavoidable responsibility in the latest scandal, with the statement adding that Tumor Biology had retracted papers over similar concerns about the peer review process in 2015.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

1. You became a LinkedIn superstar overnight。
我们不会越俎代庖,不会超越区域去做不应是中国做的事情。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: “粤派”家具行业电商起步走
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

谎言6:我29岁。说谎原因:29岁听起来比30岁要年轻多了。
Emerging market focused fund groups have endured a torrid year with sharply lower assets under management at Aberdeen and Ashmore. Emerging market exchange traded funds have also suffered heavy redemptions, with investors pulling $9.5bn from BlackRock’s iShares MSCI Emerging Markets and Vanguard’s FTSE Emerging Markets, according to ETF.com.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

['flimzi]
In the best possible way.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

加拿大学校继续失利。今年的上榜学校只有3所,而去年为5所,而且这3所学校的排名都下降了6个位次左右。多伦多大学(University of Toronto)罗特曼商学院(Rotman School of Management)排名最高,为第65位,而加拿大女王大学(Queen’s University)史密斯商学院(Smith School of Business)在今年的榜单中垫底,排名第100。
美国人:对于你们来说,干脆装成是加拿大人好了。英国人很难判断你们之间的区别,这样你们就可以避免卷入到关于死刑的尴尬谈话中了。
"The only thing she's got is the woman card," Trump said. "I'd love to see a woman president, but she's the wrong person. She's a disaster."
13. 还有更好的。10月,《洛杉矶时报》报道,平等工作机会委员会正在调查这个行业内的性别歧视现象,美国民权同盟要求各州与联邦机构继自己之后各自进行调查。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

[kru:]

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

达洛伊西奥的父母从澳大利亚搬到英国,他的父亲卢(Lou)曾在英国石油(BP)和摩根士丹利(Morgan Stanley)工作,而母亲戴安娜(Diana)是一位企业律师,同时也是儿子的合同代表。他们向来都知道达洛伊西奥是一个非常好学的孩子。但戴安娜说因为他是长子,他们本以为他不会做出什么超出寻常的事情来(达洛伊西奥有一个14岁的弟弟)。他们强调,尽管达洛伊西奥成就非凡,尽管他聊天时会聊起马尔科夫模型(Markov models)和随机过程(stochastic processes),他仍只是一个再普通不过的孩子。戴安娜说,他周末仍要出去玩,仍要去参加派对。他还有个女朋友。17岁孩子会做的事情,他都会做。
However they went ahead with plans to send 100,000 anti-Pyongyang leaflets.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

喜剧类最佳男配角:路易?安德森(Louie Anderson),《小丑梦摇篮》(Baskets)

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

But Moonlight kept pace with it over the course of a marathon four-hour ceremony. Barry Jenkins and Tarell Alvin McCraney won best adapted screenplay, while Mahershala Ali won best supporting actor — the first Oscar for a Muslim American actor.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

根据国内领先的求职平台前程无忧近日发布的一份关于2016年应届毕业生的研究报告显示,52.11%的高校毕业生已找到工作或自主创业。
3.你老板从他认识的人那收到了你认识的人给的简历。
Most of Friends was shot before cellular phones and Google were ubiquitous. The clothes and gadgets seem a bit outdated these days. Despite this, the show’s key elements still hold up remarkably well in the eyes of young viewers.
此次内衣秀将在美国时间12月4日在CBS播出。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Yes. There are plenty of positives: earnings, economic growth, and US tax cuts. But they are already known. Stocks look ridiculously expensive by historical standards, but that tells us nothing about short-term moves. Ultimately, it comes down to liquidity, which has driven markets since they emerged from the crisis in 2009. If all goes according to plan, central banks will be decreasing their balance sheets, and removing liquidity, by the end of 2018. If they go through with this, the odds are that the S&P will stall. But even a tiny tremor could make the bankers blink. Expect the momentum to continue.
对民主主义者而言,此类原始情绪的爆发之所以令人担忧是因为它们很难遏制。
显然相信“更长时间保持较低位”如今意味着“永远保持较低位”的投资者,最近几周已经涌向新兴市场资产。
'The market for colored diamonds is really, really high, because they are so rare,' he said.
9、另一地球

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

['d?kjum?nt]
[.beni'fil]

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

The girl, said to be from Shanghai, paid the man between 1,900 and 9,500 yuan every day over a two-month period through online payments using her mother's mobile phone and debit card.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

survey

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

n. 声明,陈述
专家等到夜幕降临才实施爆破,10秒钟内就夷平了十五万平方米的混凝土、玻璃、钢筋。
Rounding out our top five is Sandra Bullock, one of only two women on our list (the other is Jennifer Lawrence in 10th place). Bullock had two big hits this year in two very different genres: Gravity was a tense thriller that will likely earn her another Oscar nomination, while The Heat was a cop comedy that kicked butt at the box office, bringing in $230 million globally.
You'd love to know the balance of forces that shape and move your ponytail, right? That's why Joseph Keller, Raymond Goldstein, Patrick Warren and Robin Ball received this igNOMINIOUS prize!

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

12月8日,佳士得(Christie’s)的双年夜间拍卖会仅拍得650万英镑(含佣金),约合970万美元,而最低预估价为1270万英镑。45件作品中有19件流拍,比例达42%,包括两幅估价最高的作品——阿尔布雷特·丢勒(Albrecht Dürer)的学生汉斯·霍夫曼(Hans Hoffmann)1582年创作的水彩习作——丛林中的野兔,还有弗朗西斯科·瓜尔迪(Francesco Guardi)在18世纪70年代创作的描绘威尼斯圣乔治马焦雷岛美景的油画,这两幅画的最低估价分别是400万英镑和150万英镑。
我是否工作太辛苦了?花时间重新调整一下,花时间做令你愉快的事情是非常重要的。必要时释放你的欲望,从工作或学习压力中解脱出来,给自己时间去自由呼吸,即便一次只有几分的时间。
The Shape of Water
当其他同龄人每天乖乖去上学的时候,她已经出来养家糊口四年了,她不得不快速成熟起来。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

全食CEO约翰麦基的《自觉资本主义》(Conscious Capitalism)一书让公司高管们不得不思考这样一个观点,那就是处于最佳运转状态的企业能为所有利益相关方创造价值,而不仅仅是投资者。麦基认为,主要利益相关方包括顾客、员工、供应商、社会以及环境。他以好市多、西南航空(Southwest Airlines ,《财富》500强)和谷歌(Google,《财富》500强)为例,说明思维超越利润能够打造更强大而、更高效的公司。
['silik?n]

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

E.E.卡明斯有句话说得很有道理,“除了你自己,不要成为任何人,在这个竭尽全力、不分日夜想把你变成别人的世界里,这样做意味着迎接人类最艰苦的战斗;永不停息,战斗到底。”
“在香港地区,房地产的基本面明显放慢下来,”他说,“我减持了一点儿,然后很快发生了全面调整,所以我等到反弹后,卖出了一部分。”
今日,麦高恩在杂志Sunday Times Magazine上对性侵维权运动做出不雅评论,头一天布雷特·卡瓦诺法官刚在最高法院中宣誓就职,并于当天否认了性侵控告。
你正在寻找其他工作
何塞安东尼奥梅亚德(José Antonio Meade)会成为下一任墨西哥总统吗?

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

"The Hunger Games" star ranks first on the 2012 edition of AskMen.com's "Top 99 Most Desirable Women" list. The poll, which collected more than 2.4 million votes, asked the website's readers to choose their favorite female celebrities based on their looks, personality, talent and other desirable characteristics.
007系列电影荣誉主题曲之一:路易斯·阿姆斯特朗--《我们拥有世界上的所有时间》
IE’s online MBA consistently attracts high-calibre students. Half of IE’s alumni were senior managers when they enrolled, the highest proportion among ranked schools at that stage. Three years after graduation they were earning the highest average salary at $179,000, about $30,000 more than the next highest earners — alumni from Olin Graduate School of Business at Babson College.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

The Crown
Instead it ticked upward slightly to 8.3 per cent.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

有7所商学院在过去一两年落榜后重新上榜。
Lufax, which started four years ago has emerged as the leader due to innovative credit rating techniques.
v. 构成,把 ...

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

orig升起,开始+in→[生命]开始→起源;出身+al→起源的;独创的
Management and leadership skills are just one aspect of EMBAs. “It actually made an entrepreneur of me,” says one graduate. Nearly a third (31 per cent)of graduates have set up their own company, or are about to, since enrolling on their EMBA four or five years ago. FT data show that 91 per cent of the businesses are operating today.
Demagogues are the Achilles heel of democracy.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 合肥楼市发新政 南京房价仍火爆
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

在全球最具价值品牌百强榜上,有15个中国品牌上榜,比去年多一个,较10年前大有增加,当时中国移动(China Mobile)是唯一上榜的中国品牌。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

The International Organization for Migration says the number of migrants and refugees entering Europe in 2015 has gone over the one million mark, the largest influx of its kind since the end of World War Two.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

But the economic picture has brightened considerably in Arizona, as the housing market stabilized and unemployment hit a post-recession low of 7.8% in May. As part of Forbes’ annual Best States for Business, we look at 35 factors to determine the best and worst states, including projected employment. Arizona is expected to have the fastest job growth at 3% annually over the next five years, according to Moody’s Analytics. The job gains are projected to boost household incomes 3.6% annually through 2017, which ranks second best in the U.S. after Illinois. The added jobs also go hand-in-hand with the state’s economic growth, which Moody’s forecasts to expand at a U.S.-best 4.6% annually.
它还体现在萝塞拉·亚尔迪尼(Rossella Jardini)为莫斯奇诺(Moschino)设计的2009年春夏系列的蝴蝶结和宽松裙子上以及以玛丽·匡特(Mary Quant)为灵感的2013年春季系列中。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

下面是我对2010年美国经济以及市场前景最乐观也是最终的猜测。
根据Interbrand2016年全球最佳品牌报告显示,该榜单的前十名还包括微软、丰田汽车公司、IBM、三星电子有限公司、亚马逊、梅塞德斯-奔驰和通用电气公司。
The media are annoying, we get that, Your Royal Highness, but there may have been more dignified ways for you (and the establishment you represent) to air your concerns.
伊朗持不同政见电影人扮演一个几乎不合格的德黑兰出租车司机,带来一部狡猾的伪纪录片,深入探讨电影的悖论,以及专制统治下日常生活中的矛盾。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Fewer women than men have worked abroad for at least six months (42 per cent and 52 per cent respectively) but they share exactly the same motivations — to develop management skills, build their network and increase their earnings.
The Lego Batman Movie

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

The line of prescriptive frames and sunglasses, named “DVF | Made for Glass,” costs upwards of $1,600. Google has already partnered with Luxottica, the eyewear conglomerate behind Ray-Ban and several high-fashion eyewear offerings such as Prada. It also hired fashion executive Ivy Ross, most recently the chief marketing officer of Art.com, to lead its Glass team.
这让11月份的贸易顺差达到446.1亿美元,比10月份减少约44.5亿美元,低于预期。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 成都家居装饰装修材料合格率100%
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

10.Meditate

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

As a point of comparison, the combined 29.1 million total from those old master sales was 34 percent less than the 44.2 million Christie’s and Sotheby’s took in at equivalent events five years ago, in December 2011.
statement
“One person quit on Facebook.”
2015年,全球范围发起的233起反倾销案件中,针对金属行业的案件占比达创纪录的46%,几乎全部是针对钢铁行业的案件。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

1Switzerland
Mark Zuckerberg, CEO of Facebook Inc, said at the forum that "Artificial intelligence will understand senses, such as vision and hearing, and grasp language better than human beings over the next five to 10 years."

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

China's National Bureau of Statistics said its property prices index for November showed that new home prices fell 3.7 per cent from a year ago, the third straight annual decline following readings of -2.6 per cent in October and -1.3 per cent in September.
中国富人2014年在海外购买了至少7块小岛。
4. 《狗心》(Heart of a Dog),导演:劳瑞·安德森(Laurie Anderson)。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

"All I got was an extra hour on the bus to work, but I can't get a seat at the stadium," she said as she directed cars toward a mall's parking garage in Rio's wealthy southern zone.
Among the amenities spread through its three terminals are two 24-hour movie theaters screening the latest blockbusters for free, a rooftop swimming pool and a butterfly garden.
你咋不上天呢?

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

曼谷在2014-15年排行下降主要是由于近年来的政治不稳定。
[ri'frid.reit?]

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 莱州石材搭建“互联网+”新平台
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

6. A brand new human organ has been classified. Researchers have given the nod to the mesentery - an organ that's been hiding in plain sight in our digestive system this whole time. But that's only half the story, because we're still not sure exactly what it does.
Many economists doubt the European Central Bank will increase the size of its 1.46tn asset-purchase programme in 2016 despite assurances by ECB chief Mario Draghi that additional monetary stimulus is still on the table.
发行于2013年的《炫富帮》是一部语带讽刺的犯罪剧情片,记录了一帮好莱坞山高中生的冒险,他们偷到了当地名人的家里。少年们进入梅根·福克斯和帕丽斯·希尔顿这样的偶像家,偷走现金、衣服、手袋和珠宝,用来模仿杂志上让他们羡慕的奢华生活。在朋友圈炫耀战利品的照片后,他们终于被抓进了监狱。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 广州:公租房可“柔性退出”
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

The Post
深入推进“互联网+”行动和国家大数据战略;

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

n. 日历,月历,日程表
这一点,在他首次公开自己的性取向时表现得再突出不过了。
"Their political leanings are even affecting how they experience weather, which is pretty fascinating," said Cox.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

赢家:湖人

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Justin Bieber剃发募捐 集得4万美金
这其中包括麦肯锡(McKinsey)。去年10月,这家咨询机构的500多名高级合伙人汇聚伦敦格罗夫纳豪斯酒店(Grosvenor House Hotel),启动了神神秘秘的领导层选举程序。下一阶段涉及该公司550名高级合伙人于1月对鲍达民(Dominic Barton)继任者的候选名单进行投票,之后在2月份对两名人气最高的候选人进行第二轮投票。鲍达民自2009年起执掌麦肯锡。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 2014年是中国建材业的重大分水岭
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

单词yacht 联想记忆:
Columbia Pictures克里斯蒂安?贝尔、艾米?亚当斯和布莱德利?库珀在电影《美国骗局》中早在1月份闹片荒的时候,人们不会想到今年会迎来如此多好电影。不仅如此,有几部影片甚至达到了被我们在心目中理想化了的那些老电影的水准。今年有两部电影脱颍而出。纯娱乐片方面,赢家显然是《美国骗局》(American Hustle),这部由大卫?欧?拉塞尔(David O. Russell)执导的影片讲述了上个世纪七十年代的行骗高手和他们的微妙骗术的故事,幽默诙谐,令人捧腹。而从创新角度看,《地心引力》(Gravity)的全新拍摄技术给观众带来了新的观影体验。人们普遍认为《美国骗局》无可挑剔,这部疯狂喜剧片是一部时代佳作。我个人则认为,《地心引力》是今年的最佳影片。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

● “奥巴马总统证实,如果特朗普当选他将拒绝离开白宫”
Extreme heat blanketed Alaska and much of the western United States last year. Records were set across large areas of every inhabited continent. And the ocean surface was unusually warm virtually everywhere except near Antarctica, the scientists said, providing the energy that fueled damaging Pacific storms.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

adj. 荒谬的,可笑的
A teenage student in Southwest China's Chongqing Municipality has been sentenced to one year in jail after trying to poison fellow students for being too noisy in class, local media reported last Wednesday.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

['delikit]

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

The full list of this year's honorees follows.
The Fate of the Furious was the top-grossing foreign film, ranking second on the list.
Programming these same signals into artificial human limbs would give amputees replacement hands unlike anything we've developed before.
与此同时,还有其他因素在掣肘亚洲ETF市场,一些怀疑者担心,这些因素将阻碍散户市场的发展。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

adj. 社团的,法人的,共同的,全体的

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 北京启动治理房地产乱象行动
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

[ri'membr?ns]
10. Economics is killing the economy, but like coke addicts we won't stop
愿你一切称心如意,快乐无比。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

除了查阅综合榜单,未来的国际学生还可以缩小搜索范围,浏览某地区和某国家大学排行。这些排名仅由学校在综合榜单中的表现决定。
One fifth of the rich in the 500 list are from the information technology industry, and capital players are fading away from the list.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

A video of Bi Fujian, a popular television host, poking fun at a song from a Cultural Revolution-era opera about the Chinese civil war, with his own critical asides about Mao and the Communist Party, appeared online in April. Despite the government's efforts to contain its spread, it circulated widely, with some commenters defending Mr. Bi's opinions and his right to express them.
spontaneous

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 佛山配套利好 助推楼市
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

"The essential question of the Sino-Japanese relationship is if Japan can accept the fact that China is growing stronger and more powerful." CUI TIANKAI, member of the CPPCC National Committee and vice-minister of foreign affairs

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 喷墨印刷助力装饰装修个性飞扬
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Another exceptional new field is that of nanotechnology.
We learned about fetal surgery’s potential to change lives.
intimidating

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

However, you know when your cycles are over when the washer and dryer stop making noise. And you know when the weather is ugly by simply looking outside, or checking your weather app. Therefore, the product is basically just another way hackers can get into your home.
“LBS has a great student body, very diverse in terms of nationality, competitive and intelligent,” commented one American graduate from the class of 2012. “It also gave me the opportunity to study in the US [on exchange] without having to do a purely US-focused American MBA.”
一名11岁的女学生因发明了一个快速、廉价测试铅污染水的方法,而被誉为“美国顶尖青年科学家”。
《Look What You Made Me Do》(《看看你们都让我做了什么》)这首单曲可以载入史册了,流行音乐学者们可能会世世代代地讨论它是否是一次绝妙的公关行动。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

一些英国退欧派人士和共和党人相信绝对自由市场理念,
Social media finds you as you browse

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

我们也不希望打贸易战。我们坚持人民币汇率形成机制的改革,保持了人民币汇率在合理均衡水平上的基本稳定。
1870年3月19号,轮滑登上杂志《科学美国人》。它的制作人是伊利诺伊州奥尔尼的托马斯·呂德斯,被称作"佩德速度",后来,轮滑的轮变得小了很多,直径约为36厘米(15英寸)。吕德斯身材高大魁梧,他说自己用轮滑一直滑2个小时也不觉得累,同时他也说每一个人都可以滑轮滑,不论他们是什么体型。另一种轮滑出现在1923年,它的轮子在脚的内侧,而非外侧。(除了轮子的尺寸不一样以外,两种轮滑最主要的差别在于:由战车溜冰公司制作的轮滑,小轮在大轮的后面,增强整个轮滑的稳定性。)
周二在西弗吉尼亚州的贝灵顿一个人在雪地里行走。星期二飓风桑迪使得西弗吉尼亚州的部分地区被超过一英尺的雪所覆盖。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

清华大学的毕业生以毕业五年后平均月薪14822元高居榜首。39所高校生跻身万元户行列。此外,共有185所高校的毕业生平均月薪突破8000元大关,789所高校的平均月薪突破了6000元大关。
US president Donald Trump’s zero-sum, Art-of-the-Deal approach to negotiation will give comfort to old-fashioned incumbents. I am hoping 2018 will provide an opportunity for positive, problem-solving new leaders to emerge. But change could stall if business chiefs, disheartened by the poor quality of political leadership, turn inwards instead.

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